- Chromoblastomycosis is a chronic subcutaneous mycotic infection caused by saprophytic moulds ubiquitous in the environment.
- The most common etiologic agents are Fonsecaea pedrosoi and Cladophialophora carrionii, both of which can be isolated from plant debris.
- The infection usually follows traumatic inoculation through penetrating thorn or splinter wounds.
- The fungal agents develop as small clusters of cells known as muriform bodies.
- Several months after the injury, painless papules or nodules appear in the affected area progressing to scaly and verrucose plaques.
- Direct examinations of skin scrapings or histopathologic study demonstrate the typical muriform bodies.
- Microbiologic culture is necessary for the correct determination of the etiologic agent.
- Itraconazole is the treatment of choice, often in combination with surgery.
- Even so, results are often unsatisfactory as patients present late to medical services because of lack of funds and the fact that the disease usually affects the main family earner.